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Chronic Hepatitis B : Functional Cure is here but examining the liver matters
"We have not had a treatment which has come to this level of cure." — Prof. Lim Seng Gee National University Health System, Singapore Functional cure significantly reduces liver complications including liver cancer. Consequences of Chronic Hepatitis B Infection GSK’s bepirovirsen leads to high rates of functional cure (read the full report at CNN Health) However, the exact mechanism by which this happens is unclear. Investigating the liver using liver biopsies is crucial to u
Breakthrough Liver Biopsy Innovation Unveiled at NIC Conference, 13 – 15 November 2025
Dr Mangat presenting VABS™ at NIC Conference Dr Mangat sharing with the audience at NIC Conference on the rising prevalence of liver disease and how iRnovate's VABS™ could help reshape the future of liver disease diagnostics. At this year’s NIC Conference organised by NUS Medicine International Council, Dr Kamarjit Singh Mangat, Senior Consultant at the Division of Interventional Radiology, Department of Diagnostic Imaging, National University Hospital, delivered a compelling
Interesting read from The Lancet July 28, 2025
“There is an urgent need for more accessible, informed screening for cirrhosis in people with MASLD or MASH, as well as the development of better tools to identify patients with MASLD or MASH, who do not have cirrhosis, who could benefit from targeted liver cancer surveillance.” iRnovate is moving into human trials with a low risk liver biopsy tool that provides high quality liver tissue samples for timely diagnosis and intervention. Exciting news that promises to change the
Millions in west do not know they have aggressive fatty liver disease, study says
https://www.theguardian.com/society/2025/jun/05/millions-in-west-do-not-know-they-have-aggressive-fatty-liver-disease-study-says
iRnovate Pte. Ltd. signs agreement with NUH and NUS for global exclusive rights to exploit VABS patents
iRnovate Pte. Ltd. signs agreement with NUH and NUS for global exclusive rights to exploit VABS patents
Dr Kam Mangat secures GAP Grant of $260k
Dr Kam Mangat secures GAP Grant of $260k
‘Coffee Shop King’ died of haemorrhage after liver biopsy; death a medical misadventure
https://www.straitstimes.com/singapore/courts-crime/coffee-shop-king-died-of-haemorrhage-after-liver-biopsy-death-a-medical-misadventure
iRnovate Pte. Ltd. incorporated (Singapore) and seed funding secured for animal and FIH trial preparation
iRnovate Pte. Ltd. incorporated (Singapore) and seed funding secured for animal and FIH trial preparation.
Dr Kam Mangat secures Kickstart Grant of $500k
Dr Kam Mangat secures Kickstart Grant of $500k
Dr Kam Mangat secures Innovation2Start SMART grant$1.25m in 3 stages
(only SMART phase $250k used)
Dr Kam Mangat secures NUHS-NHIC Joint Medtech grant $100k
approximately S50k used as MERCI disbanded by NUS.
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